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Ambien (zolpidem tartrate) is indicated for the short-term treatment of insomnia characterized by difficulties with sleep initiation. Ambien has been shown to decrease sleep latency for up to 35 days in controlled clinical studies.

The clinical trials performed in support of efficacy were 4–5 weeks in duration with the final formal assessments of sleep latency performed at the end of treatment.


Use the lowest effective dose for the patient. The recommended initial dose is 5 mg for women and either 5 or 10 mg for men, taken only once per night immediately before bedtime with at least 7–8 hours remaining before the planned time of awakening. If the 5 mg dose is not effective, the dose can be increased to 10 mg. In some patients, the higher morning blood levels following use of the 10 mg dose increase the risk of next day impairment of driving and other activities that require full alertness. The total dose of AMBIEN should not exceed 10 mg once daily immediately before bedtime.

The recommended initial doses for women and men are different because zolpidem clearance is lower in women.

Side Effects

Seek emergency medical help right away if you have any of these signs of an allergic reaction to Ambien:

  • Hives
  • Trouble breathing
  • Swelling of your tongue, throat, or face
  • Nausea
  • Vomiting

Serious side effects of Ambien are:

  • Getting out of bed while not being fully awake and performing an activity that you are not aware you are doing, such driving a vehicle, sleep-walking, preparing and eating food, making phone calls, or having sex Abnormal thoughts or behaviors, such as aggressiveness, abnormal extroversion, confusion, agitation, hallucinations, worsening of depression, or suicidal thoughts or actions
  • Memory loss
  • Anxiety
  • Sleepiness during the day

Common side effects of Ambien are:

  • Drowsiness
  • Tiredness
  • Sleepiness during the day
  • Dizziness
  • Drugged feelings
  • Nausea
  • Diarrhea
  • Headache

Call your doctor if you experience any of the following mouth side effects after taking Edluar (zolpidem sublingual tablets):

  • Tender red bumps under the tongue
  • Tingling, tickling, prickling, pricking, or burning of the tongue